Venlafaxine ER (generic Effexor XR®)

Starting at $24 for a 30-day supply
Free 2-day shipping
No insurance required

Venlafaxine ER is an extended release prescription antidepressant. It can help lift persistent depression, reduce anxiety, and ease the fear and worry that come with panic and social anxiety disorder.

• Get care from a real doctor, without leaving home
• Same-day prescriptions available
• Medication delivered free, straight to your door

Book a visit to meet with a QuickMD doctor for a venlafaxine ER prescription or refill

A QuickMD doctor can prescribe medication only after your visit, and prescriptions aren't guaranteed. The listed price covers medication only and doesn't include the cost of your doctor visit.

You deserve to feel good every day

Get venlafaxine prescribed online from the comfort of home.
$99 visit fee—no insurance required.

Getting started with venlafaxine at QuickMD

Description
Venlafaxine ER is an FDA-approved SNRI (serotonin-norepinephrine reuptake inhibitor) used to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder, and panic disorder. The extended-release formulation delivers the medication gradually over time. When prescribed appropriately, patients may notice a meaningful reduction in persistent sadness and excessive worry.

How to use

Take venlafaxine by mouth once a day with food, at the same time each day, or as directed by your QuickMD doctor. If you are taking the extended-release capsule, swallow it whole. Do not crush, chew, or open it. Venlafaxine should always be taken with food to help reduce nausea. Do not take it more often than directed, and do not stop taking it suddenly without speaking to your doctor first.

Benefits

Venlafaxine ER may provide the following benefits:

• Lifted mood and reduced feelings of persistent sadness or hopelessness
• Reduced excessive worry and a greater sense of calm
• Less fear and self-consciousness in social situations
• Fewer and less intense panic attacks
• Effective for patients who have not responded well to SSRIs alone

Benefits and treatment outcomes vary from person to person.

Side effects

Serious or adverse side effects from venlafaxine are rare. However, some patients may experience:

• Nausea
• Headache
• Dry mouth
• Dizziness
• Trouble sleeping
• Constipation
• Increased sweating
• Reduced sex drive

Venlafaxine may also cause a modest increase in blood pressure in some patients. Contact your doctor right away if you experience signs of serotonin syndrome (a rare but serious reaction that can include rapid heart rate, confusion, and muscle twitching), unusual bleeding, or worsening depression.

This is not a full list of side effects, interactions, or warnings, and it should not replace medical advice. For guidance tailored to your health and medications, always talk with your healthcare provider or pharmacist.

Safety information

Venlafaxine must be prescribed by a licensed doctor. Like any medication, venlafaxine comes with important safety considerations, including possible side effects, serious risks, and certain conditions where it may not be safe to use. Venlafaxine should never be stopped suddenly and must be tapered under medical guidance.

Venlafaxine may not be appropriate if you:

• Are taking or have recently taken an MAO inhibitor (such as phenelzine or selegiline)
• Are taking linezolid or methylene blue
• Have a known allergy or hypersensitivity to venlafaxine
• Have uncontrolled high blood pressure or a history of cardiovascular disease
• Have a history of seizures or bipolar disorder, without first discussing risks with your doctor
• Have narrow-angle glaucoma
• Are pregnant, planning to become pregnant, or breastfeeding, without first discussing risks with your doctor

This is not a complete list of precautions, contraindications, or drug interactions. Always talk with your healthcare provider or pharmacist about your medical history and any medications or supplements you are taking before starting venlafaxine.

Venlafaxine ER (Effexor XR®)

$24/30-day supply starting price

Start feeling better mentally and emotionally. Meet with a QuickMD doctor and, if appropriate, receive a prescription for venlafaxine ER. No insurance required.

• Support your mental health with proven treatment
• Same-day prescriptions available after your visit
• Delivered straight to your door when prescribed

Frequently asked questions

Should I take venlafaxine in the morning or at night?

Some patients find it works best in the morning, particularly if it affects their sleep. Others prefer taking it at night if they notice any drowsiness. The most important thing is to take it at the same time each day and always with food to help reduce nausea.

Does venlafaxine cause weight gain?

Weight changes are possible with venlafaxine, though they tend to be modest and vary from person to person.

How long does venlafaxine stay in your system?

Venlafaxine works relatively quickly in the body and clears out faster than many other antidepressants. In most patients, venlafaxine may fully clear from the system within a few days of stopping.

Start treatment with venlafaxine ER online

Book your first visit

Getting started begins with a simple online visit. You'll meet with a licensed QuickMD doctor from the comfort of home, where you can talk openly about what you've been going through and what kind of support you're looking for.

Learn more about venlafaxine

Your doctor will take time to understand any challenges you're facing, your mental health history, and what you've tried so far. If venlafaxine ER is appropriate, they'll guide you through how it works in your body, how to take it, what to expect, and how it can help reduce the anxiety, fear, and low mood that can get in the way of your daily life.

Get your medication delivered

If your doctor prescribes venlafaxine ER, your prescription is sent directly to our pharmacy partner and shipped straight to your door. You'll receive clear instructions on how to take it.